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Barbiturates have minor analgesic action at subanesthetic doses. Fairly, in subanesthetic doses these medication may raise the response to agonizing stimuli. All barbiturates exhibit anticonvulsant action in anesthetic doses.
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Withdrawal signs or symptoms take place in infants born to mothers who acquire barbiturates all over the final trimester of pregnancy.
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Maximal CNS depression may not manifest until 15 minutes or maybe more after IV administration for phenobarbital sodium.
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This system is probably through the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the medical reaction to doxycycline needs to be monitored closely.